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. 2021 Feb;10(2):643–653. doi: 10.21037/tau-20-1169

Figure 6.

Figure 6

CTGF and ZEB1 are targets of miR-656-3p and miR-485-5p. (A) Potential miR-656-3p and miR-485-5p binding sequences in 3’UTR of CTGF and ZEB1 mRNA. (B) Predicted miR-656-3p and miR-485-5p binding sites in 3’UTR of CTGF and ZEB1 mRNA were verified by luciferase reporter assay. (C,D) Regulation of CTGF and ZEB1 protein levels by TGF-β1, resveratrol, DIO3OS, miR-656-3p and miR-485-5p was determined by Western blot assay. (E,F) Regulation of CTGF and ZEB1 protein levels by TGF-β1, resveratrol, DIO3OS, miR-656-3p and miR-485-5p was tested by Western blot assay. wt, wild type; mut, mutant type; *, P<0.05.