Table 1. Demographics and clinical characteristics of patients enrolled in the study.
| Patients with CAH | Patients without CAH | ||||
|---|---|---|---|---|---|
| TART (n=16), n (%) or median [range] | No TART (n=36), n (%) or median [range] | P | Control group (other testicular masses; n=16), n (%) or median (range) | P (comparison with TART group) |
|
| Age (years) | 23.5 [18–43] | 22 [16–48] | 0.538 | 36.5 [13–75] | 0.010 |
| SW | 15 (93.8) | 13 (36.1) | <0.001 | – | – |
| SV | 0 | 10 (27.8) | 0.019 | – | – |
| NC | 1 (6.2) | 13 (36.1) | 0.025 | – | – |
| ACTH (pg/mL) | 190 [5–2,258] | 34.5 [5–2,160] | 0.019 | ||
| Age at diagnosis | 19 [17–40] | – | – | 36.5 [13–75] | 0.003 |
| Final diagnosis | TART | No TART | – | 8 leydigioma; 5 seminoma; 3 mixed germ cell tumors§ |
– |
§, Mixed germ cell tumors: seminomatous and non-seminomatous germ-cell tumors. CAH, congenital adrenal hyperplasia; TART, testicular adrenal rest tumor; SW, salt-wasting; SV, simple virilizing; NC, non-classic; ACTH, adreno-cortico-tropic hormone.