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. 2021 Feb;13(2):689–707. doi: 10.21037/jtd-20-2909

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2021 Journal of Thoracic Disease. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

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The relative expression of pleckstrin homology domain family A (PHLDA) genes in normal and lung adenocarcinoma (LUAD) tissues according to The Cancer Genome Atlas (TCGA) datasets and the relative expression of PHLDA genes in normal and malignant mesothelioma (MM) tissues according to GSE51024 raw data. (A) PHLDA1, (B) PHLDA2, and (C) PHLDA3 in LUAD subtype tissue, (D) PHLDA1, (E) PHLDA2, and (F) PHLDA3 in MM tissue. (A) All PHLDA genes were highly expressed in LUAD when compared to normal tissue. (D) PHLDA1 gene expression in MM was lower than in normal tissue; (F) PHLDA3 gene expression was significantly higher than in normal tissue; (E) no statistical difference was found for PHLDA2 expression between MM and normal samples.