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. 2021 Feb;13(2):689–707. doi: 10.21037/jtd-20-2909

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2021 Journal of Thoracic Disease. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

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This Kaplan Meier survival curve shows the correlation between pleckstrin homology domain family A (PHLDA) genes expression and overall survival (OS) in malignant mesothelioma patients according to the The Cancer Genome Atlas (TCGA) Firehose Legacy datasets. (A) High expression of the PHLDA1 (HR=1.80, 95% CI: 1.1–2.9; P=0.01) and (B) PHLDA2 (HR=1.87, 95% CI: 1.2–3.0; P<0.01) genes was significant correlated with worse OS; (C) PHLDA3 gene expression was not correlated with survival (HR =1.29, 95% CI: 0.8–2.1; P=0.27).