Table 3. Clinicopathological characteristics of the patients with malignant mesothelioma from TCGA database (Chi-square test; P value <0.05).

Parameters	PHLDA1							PHLDA2							PHLDA3
	High			Low		P value		High			Low		P value		High			Low		P value
	N	%		N	%			N	%		N	%			N	%		N	%
Age						0.23							0.05							0.05
≤50 years	2	4.7		5	11.4			6	14.0		1	2.3			6	14.0		1	2.3
>50 years	41	95.3		39	88.6			37	86.0		43	97.7			37	86.0		43	97.7
Race category						1.00							1.00							1.00
Asian	1	2.3		0	0.0			0	0.0		1	2.3			1	2.3		0	0.0
Black or African American	0	0.0		1	2.3			0	0.0		1	2.3			0	0.0		1	2.3
White	42	97.7		43	97.7			43	100.0		42	95.5			42	97.7		43	97.7
Gender						0.29							0.61							0.09
Female	6	14.0		10	22.7			7	16.3		9	20.5			11	25.6		5	11.4
Male	37	86.0		34	77.3			36	83.7		35	79.5			32	74.4		39	88.6
Tumor size						0.72							0.60							0.01
1	7	16.3		7	15.9			6	14.0		8	18.2			3	7.0		11	25.0
2	12	27.9		14	31.8			16	37.2		10	22.7			18	41.9		8	18.2
3	18	41.9		14	31.8			15	34.9		17	38.6			18	41.9		14	31.8
4	5	11.6		8	18.2			6	14.0		7	15.9			4	9.3		9	20.5
TX	1	2.3		1	2.3			0	0.0		2	4.5			0	0.0		2	4.5
Lymph node status						0.73							0.06							0.02
Negative	22	51.2		22	50.0			25	58.1		19	43.2			27	62.8		17	38.6
Positive	18	41.9		21	47.7			14	32.6		25	56.8			14	32.6		25	56.8
NX	3	7.0		1	2.3			4	9.3		0	0.0			2	4.7		2	4.5
Metastasis status						0.55							0.47							0.63
Negative	27	62.8		30	68.2			27	62.8		30	68.2			33	76.7		24	54.5
Positive	1	2.3		2	4.5			2	4.7		1	2.3			2	4.7		1	2.3
MX	15	34.9		12	27.3			14	32.6		13	29.5			8	18.6		19	43.2
Stage						0.61							0.53							0.05
I	6	14.0		4	9.1			6	14.0		4	9.1			3	7.0		7	15.9
II	6	14.0		10	22.7			10	23.3		6	13.6			12	27.9		4	9.1
III	24	55.8		21	47.7			20	46.5		25	56.8			23	53.5		22	50.0
IV	7	16.3		9	20.5			7	16.3		9	20.5			5	11.6		11	25.0
TP53 status						0.39							0.73							<0.01
Wild type	38	88.4		36	81.8			36	83.7		38	86.4			41	95.3		33	75.0
Mutated	5	11.6		8	18.2			7	16.3		6	13.6			2	4.7		11	25.0

PHLDA, pleckstrin homology domain family A.