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. 2021 Feb;13(2):541–551. doi: 10.21037/jtd-20-2552

Table 3. Demographics and clinical characteristics of patients with pulmonary embolism group by mortality.

Variables Non-survivors (n=49) Survivors (n=586) P value
General information
Age, years 68.15±16.47 57.37±16.63 <0.001
Female gender 12 (24.5) 257 (43.9) 0.008
Smoking status 0.67
   Smoker/ever smoker 12 (24.5) 160 (27.3)
   Non-smoker 37 (75.5) 426 (72.7)
Body mass index 22.67±3.54 23.83±4.07 0.183
Presenting manifestation
   Dyspnea 44 (89.8) 397 (67.9) <0.001
   Pleuritic chest pain 5 (10.2) 216 (36.9) <0.001
   Hemoptysis 6 (12.2) 161 (27.5) 0.02
   Leg pain or swelling 19 (38.8) 185 (31.6) 0.299
   Syncope 15 (30.6) 73 (12.5) <0.001
   Fever 7 (14.9) 40 (7.1) 0.053
Predisposing or comorbid condition
   Immobilization 18 (36.7) 180 (30.7) 0.382
   Trauma 1 (2.0) 7 (1.2) 0.476
   Cancer 12 (24.5) 109 (18.6) 0.313
   Stroke 5 (10.2) 38 (6.5) 0.366
   Chronic pulmonary disease* 21 (42.9) 175 (29.9) 0.059
   Pulmonary tuberculosis 5 (10.2) 27 (4.6) 0.091
   Congestive heart failure 9 (18.4) 2 (5.5) <0.001
Vital signs
   Blood pressure
    Hypotension, systolic blood pressure 6 (12.8) 33 (5.8) 0.061
    Normal blood pressure or hypertension 41 (87.2) 533 (94.2) 0.061
   Heart rate 97.62±22.98 86.59±15.79 0.002
   Respiratory rate 21.45±4.45 20.66±2.66 0.236
   SpO2 92.33±5.71 94.75±5.57 0.047
SPESI <0.001
   High risk 41 (83.7) 337 (57.5)
   Low risk 8 (16.3) 249 (42.5)
Laboratory findings
   WBC (×10^9/L) 10.68 (7.42–12.86) 7.84 (5.64–10.75) <0.001
   PLT (×10^9/L) 115 [78–190] 177 [132–243] <0.001
   NT- proBNP (pg/mL) 2800 (889.25–8,085.5) 425 (106.5–2,163.5) <0.001
   Troponin T (ng/L) 69.45 (33.45–269.95) 16.3 (7.30–38.00) <0.001
   CK-MB (ng/mL) 4.51 (1.97–13.99) 1.55 (0.90–3.32) <0.001
Radiologic findings
   Pleural effusion 36 (73.5) 327 (55.8) 0.016
   Small pleural effusion 35 (97.2) 320 (97.9) 0.805
   Mass pleural effusion 1 (2.8) 7 (2.1) 0.570
   Location of the largest pulmonary emboli (bilateral) 29 (59.2) 299 (51.2) 0.283
   Deep vein thrombosis 4 (57.1) 232 (56.2) 1
   Right ventricle dilation on computed tomography 18 (37.5) 184 (31.4) 0.383
   Pulmonary infarction 9 (18.8) 137 (23.4) 0.464
Clinical outcome
   Respiratory failure 24 [49] 80 (13.7) <0.001
   Systemic thrombolysis 0 (0) 1 (0.3) 1
   Length of hospital stay, days 18.76±21.40 17.90±19.57 0.810
   Mechanical ventilation 9 (18.4) 12 (2.0) <0.001
   Tracheal intubation 7 (50.0) 5 (5.7) <0.001
   Hospital bleeding 7 (28.0) 27 (14.6) 0.142