Table 3. Baseline demographic, clinical characteristics and laboratory data of the matched patients.
| Characteristics | Total | Vitamin C (n=35) | Non vitamin C (n=35) | P value |
|---|---|---|---|---|
| Age | 59±17 | 60±15 | 59±18 | 0.95 |
| Sex, male | 45 (64.3) | 27 (77.1) | 18 (51.4) | 0.03 |
| Comorbidities | ||||
| Diabetes | 15 (21.4) | 6 (17.1) | 9 (25.7) | 0.38 |
| Heart failure | 2 (2.9) | 1 (2.9) | 1 (2.9) | >0.99 |
| Chronic kidney disease | 4 (5.7) | 2 (5.7) | 2 (5.7) | >0.99 |
| Chronic lung disease | 18 (25.7) | 7 (20.0) | 11 (31.4) | 0.27 |
| Liver cirrhosis | 2 (2.9) | 2 (5.7) | 0 (0) | 0.49 |
| Stroke | 2 (2.9) | 2 (5.7) | 0 (0) | 0.49 |
| Malignancy | 2 (2.9) | 1 (2.9) | 1 (2.9) | >0.99 |
| Immunocompromised | 42 (60.0) | 18 (51.4) | 24 (68.6) | 0.14 |
| Organ transplantation | 6 (8.6) | 3 (8.6) | 3 (8.6) | >0.99 |
| Others | 20 (28.6) | 9 (25.7) | 11 (31.4) | 0.60 |
| WBC, /µL | 18,675±45,575 | 10,341±7,934 | 27,008±63,333 | 0.13 |
| CRP, mg/dL | 15±10 | 15±9 | 14±11 | 0.84 |
| Procalcitonin, ng/mL | 3±8 | 3±8 | 3±7 | 0.93 |
| Acute kidney injury | 35 (50.0) | 17 (48.6) | 18 (51.4) | 0.81 |
| CRRT | 33 (47.1) | 17 (48.6) | 16 (45.7) | 0.81 |
| Vasopressors | 47 (67.1) | 26 (74.3) | 21 (60.0) | 0.20 |
| Steroid | 59 (84.3) | 31 (88.6) | 28 (80.0) | 0.32 |
| ECMO | 14 (20.0) | 10 (28.6) | 4 (11.4) | 0.07 |
| APACHE scores | 27±10 | 25±9 | 30±10 | 0.03 |
| Day 1 SOFA scores | 10±4 | 10±4 | 10±4 | 0.46 |
Data are presented as mean ± standard deviation or number (%), unless otherwise indicated. WBC, white blood cell; CRP, C-reactive protein; ECMO, extracorporeal membrane oxygenation; APACHE, acute physiology and chronic health evaluation; SOFA, sequential organ failure assessment.