Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Feb 25;11:621098. doi: 10.3389/fimmu.2020.621098

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2021 Akiyama, Ohtsuki, Berry, Liang, Goronzy and Weyand

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Innate Immune Cells in Giant Cell Arteritis. Tissue sections from temporal artery biopsies were stained for the dendritic cell (DC) marker DC-SIGN (A) and the macrophage marker CD68 (B) and visualized by immunofluorescence imaging. Nuclei marked by DAPI. In the healthy artery, the autofluorescent lamina elastica interna separates the media and intima. DC-SIGN⁺ dendritic cells are positioned at the adventitial-medial border. In the vasculitis-affected artery, DC-SIGN⁺ dendritic cells expand in the adventitia. CD68⁺ macrophages are essentially undetectable in the healthy artery but occupy all wall layers of the GCA artery. Int, intima; Med, media; Adv, adventitia. Scale Bar; 50 μm.