TABLE 1.
Experiment | Ischemia | Wnt signaling |
In vitro | CTRL | EtOH |
4OHT | ||
MCAO | EtOH | |
4OHT | ||
In vivo | CTRL | CO |
TAM | ||
MCAO | CO | |
TAM |
Altogether eight different combinations of treatments were used in our analyses, depending on the type of an experiment, the (patho)physiological conditions of the brain, and the state of the canonical Wnt signaling pathway. 4OHT, (Z)-4-hydroxytamoxifen; CO, corn oil; CTRL, control; EtOH, ethanol; MCAO, middle cerebral artery occlusion; TAM, tamoxifen.