Table 2.
Intra-group analysis in MFSN group at the three time points. Characteristic: variable taken into account;
p-value: test p-value (see the text for abbreviations and further details)
| Characteristic | Time T0 | Time T1 | Time T2 | p-value | Post-hoc analysis | ||
| T0 vs T1 | T1 vs T2 | T0 vs T2 | |||||
| Compliance | 0.9999 | ||||||
| good | 24 (100%) | 24 (100%) | |||||
| Tolerability | 0.9999 | ||||||
| good | 22 (91.67%) | 19 (79.17%) | |||||
| fairly good | 2 (8.33%) | 5 (20.83%) | |||||
| Decongestants use | 9 (37.5%) | 2 (8.33%) | 1 (4.17%) | 0.0008 | 0.0469 | 0.9999 | 0.0234 |
| Systemic antihistamines use | 7 (29.17%) | 2 (8.33%) | 0 (0%) | 0.0076 | 0.3750 | 0.9999 | 0.0469 |
| SIGNS | |||||||
| Turbinate Hypertrophy | 24 (100%) | 24 (100%) | 14 (58.33%) | <0.0001 | 0.9999 | 0.0059 | 0.0059 |
| Watery Rhinorrhea | 14 (58.33%) | 11 (45.83%) | 7 (29.17%) | 0.0581 | |||
| Post-Nasal Drip | 12 (50%) | 11 (45.83%) | 3 (12.5%) | 0.0013 | 0.9999 | 0.0645 | 0.0352 |
| Pale Mucosa | 18 (75%) | 15 (62.5%) | 7 (29.17%) | 0.0010 | 0.9999 | 0.0234 | 0.0103 |
| NASAL AIRFLOW | |||||||
| Inspiratory Resistance | 0.96 (0.33) | 0.55 (0.27) | 0.39 (0.16) | <0.0001 | <0.0001 | <0.0001 | <0.0001 |
| Expiratory Resistance | 1.05 (0.34) | 0.61 (0.26) | 0.46 (0.17) | <0.0001 | 0.0001 | <0.0001 | 0.0001 |
| Nasal Decongestant Test Insp. | 0.59 (0.27) | 0.41 (0.18) | 0.34 (0.16) | <0.0001 | <0.0001 | <0.0001 | <0.0001 |
| Nasal Decongestant Test Exp. | 0.66 (0.28) | 0.44 (0.18) | 0.38 (0.15) | <0.0001 | <0.0001 | <0.0001 | <0.0001 |
| SYMPTOMS | |||||||
| VAS Nasal Discomfort | 5.29 (3.79) | 2.74 (2.63) | 0.95 (1.66) | <0.0001 | 0.0848 | 0.0794 | 0.0013 |
| VAS Nasal Obstruction | 7.3 (2.28) | 2.65 (1.61) | 0.85 (1.38) | <0.0001 | 0.0262 | 0.0143 | <0.0001 |
| VAS Rhinorrhea | 5.47 (3.52) | 1.78 (1.9) | 0.37 (0.8) | <0.0001 | 0.0157 | 0.8538 | 0.0001 |
| VAS Itching | 3.74 (3.83) | 0.9 (1.48) | 0.01 (0.04) | <0.0001 | 0.0035 | <0.0001 | <0.0001 |
| VAS Sneezing | 5.17 (3.48) | 1.1 (1.68) | 0.04 (0.18) | <0.0001 | 0.0074 | 0.0724 | <0.0001 |
| VAS Post-nasal Drip | 3.93 (3.56) | 1.54 (1.53) | 0.27 (0.66) | <0.0001 | 0.0051 | 0.7815 | <0.0001 |
| VAS Olfaction | 2.48 (2.67) | 0.93 (1.29) | 0.38 (0.75) | <0.0001 | 0.0121 | 0.4667 | <0.0001 |
| VAS Snoring | 1.92 (2.48) | 0.8 (1.2) | 0.25 (0.53) | 0.0001 | 0.0392 | 0.0828 | <0.0001 |
| VAS Bronchial Discomfort | 0.58 (1.53) | 0.55 (1.4) | 0.34 (1.06) | 0.0498 | 0.0001 | <0.0001 | <0.0001 |
| VAS Ocular Discomfort | 0.9 (2.16) | 0.3 (1.03) | 0 (0) | 0.0545 | |||
| VAS Quality of Life | 7.78 (2.35) | 2.3 (1.74) | 0.82 (1.4) | <0.0001 | <0.0001 | 0.0085 | 0.0037 |
| VAS Quality of Sleep | 7.97 (2.23) | 2.33 (1.97) | 0.8 (1.42) | <0.0001 | <0.0001 | 0.0067 | 0.0030 |
| VAS Impact on Daily Activities | 7.82 (2.44) | 1.98 (1.83) | 0.69 (1.29) | <0.0001 | 0.0001 | 0.0088 | 0.0003 |