Table 5.
Area under the curve for plasma glucose, insulin, ghrelin, glucagon-like peptide-1, and peptide YY after glucose and sucrose ingestion in males and females
| Male | Female | P S × sex | |||||
|---|---|---|---|---|---|---|---|
| Glucose drink | Sucrose drink | P | Glucose drink | Sucrose drink | P | ||
| Glucose, mg/dL·min | 14 170.76 (12 803.66-15 204.15) | 12 416.06 (11 293.88-13 810.34) | < .001a | 13 601.18 (12 465.00-15 538.34) | 12 928.98 (11 856.36-14 290.73) | < .001a | .82 |
| Insulin, µU/mL·min | 7797.36 (5481.36-9513.27) | 5068.72 (4508.60-7949.36) | < .001a | 8726.71 (6416.37-13 635.52) | 6304.22 (4402.47-9860.87) | < .001a | .41 |
| Acyl-ghrelin, pg/mL·min | 7151.43 (5253.65-11 127.90) | 7846.65 (5739.83-12 603.78) | .69 | 9501.78 (5230.30-13 306.05) | 9691.73 (6042.45-12 483.66) | .72 | .90 |
| GLP-1(7–36), pg/mL·min | 1524.10 (904.00-2111.15) | 876.30 (309.65-1570.08) | < .001a | 1361.90 (830.56-2071.20) | 952.75 (642.51-1436.01) | .02a | .01a |
| PYY(total), pg/mL·min | 8548.16 (6826.03-12 653.67) | 8555.00 (6097.26-12 464.78) | .33 | 8603.44 (5994.90-10 799.97) | 7600.76 (5187.50-9483.62) | .03a | .46 |
Data are median (25th percentile-75th percentile).
Abbreviations: GLP-1, glucagon-like peptide-1; PYY, peptide YY.
a P values are statistically significant between glucose and sucrose drinks. Adjusted for age, sex, and body mass index. PS X sex, P value for sugar × sex interaction, statistical significance if P less than .05.