Table 3.
Multivariate analysis of factors for the prediction of overall survival.
| β | HR | 95.0% CI | P | ||
|---|---|---|---|---|---|
| Lower | Upper | ||||
| Gender, (male vs. female) | 0.589 | 1.802 | 1.102 | 2.947 | 0.019 |
| Neutrophil absolute value, (>5.8 vs. ≤5.8 ×109/L) | 0.518 | 1.678 | 1.053 | 2.676 | 0.030 |
| KPS, (<80 vs. ≥80) | 0.591 | 1.806 | 1.086 | 2.737 | 0.023 |
| Hb level, (<120 vs. ≥120 g/L) | 0.475 | 1.608 | 1.138 | 2.271 | 0.007 |
| PLT count, (>220 vs. ≤ 220 ×109/L) | 0.470 | 1.601 | 1.173 | 2.185 | 0.003 |
| No. of chemotherapy cycles, (<4 vs. ≥4) | 0.339 | 1.404 | 1.014 | 1.943 | 0.041 |
| Radiotherapy dose, (<60 vs. ≥60Gy) | 0.290 | 1.336 | 0.957 | 1.865 | 0.089 |
| Total number of metastases, (≥5 vs.<5) | 0.318 | 1.374 | 0.933 | 2.025 | 0.108 |
| WBC count, (≤ 7.6 vs. >7.6 ×109/L) | 0.218 | 1.243 | 0.841 | 1.839 | 0.276 |
| No. of metastatic organs, (≥2 vs. <2) | 0.046 | 1.047 | 0.697 | 1.573 | 0.826 |
| History of smoking, (No vs. Yes) | 0.113 | 1.120 | 0.714 | 1.756 | 0.621 |
| Neutrophil-to-lymphocyte ratio, (>4.30 vs. ≤4.30) |
0.170 | 1.186 | 0.804 | 1.747 | 0.390 |
| LDH, (>165 vs. ≤ 165 IU/L) | 0.063 | 1.065 | 0.746 | 1.521 | 0.729 |
| ALP level, (>99 vs. ≤ 99 IU/L) | 0.022 | 1.022 | 0.743 | 1.406 | 0.895 |
| Lymphocyte absolute value, (≤0.93 vs. >0.93 ×109/L) |
0.054 | 1.055 | 0.682 | 1.631 | 0.810 |
| D-Dimer (≥0.5 vs.<0.5 mg/L) | 0.067 | 1.070 | 0.786 | 1.456 | 0.669 |
| Fibrinogen (>4.50 vs. ≤4.30 g/L) | 0.105 | 1.111 | 0.786 | 1.570 | 0.551 |
| Albumin (≤40 vs. >40 g/L) | 0.021 | 1.021 | 0.702 | 1.485 | 0.914 |
| Brain metastasis (Yes vs. No) | 0.177 | 1.193 | 0.863 | 1.649 | 0.284 |
| Bone metastasis (Yes vs. No) | 0.003 | 1.003 | 0.703 | 1.432 | 0.985 |
| T stage (T1-2 vs, T3-4) | 0.029 | 1.030 | 0.723 | 1.467 | 0.871 |
CI, confidence interval.