Table 1.
Univariate cox proportional hazards analysis of clinical parameters and m6A risk score level of glioblastoma (GBM) patients in the training set and validation set.
Variables | Training set | Validation set | |||
---|---|---|---|---|---|
Univariate analysis | Univariate analysis | ||||
HR(95%CI) | P-value | HR(95%CI) | P-value | ||
Age group | Younger vs old | 0.41(0.286-0.61) | 6.7e-06 | 1.24(0.87-1.76) | 0.217 |
CIMP status | G-CIMP vs NON | 1.63(0.96- 2.78) | 0.068 | / | / |
Gender | Male vs Female | 1.04(0.78- 1.40) | 0.764 | 0.91(0.63-1.32) | 0.642 |
Subtype | NE+PE vs CL+ME | 1.15(0.80- 1.64) | 0.437 | / | / |
m6Arisk group | Low vs High | 0.48(0.34- 0.70) | 8.67e-05 | 0.53 (0.32-0.86) | 0.0103 |
Radiotherapy | Yes vs No | / | / | 0.51(0.26-1.02) | 0.05 |
Chemotherapy | Yes vs No | / | / | 0.59(0.30-1.18) | 0.139 |
IDH status | Wildtype vs Mutant | / | / | 1.45(0.83-2.53) | 0.190 |
1p19q status | Non vs Codel | / | / | 1.20(0.48-2.97) | 0.690 |
Bold values are statistically significant.