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. 2021 Feb 25;11:632934. doi: 10.3389/fonc.2021.632934

Table 1.

Univariate cox proportional hazards analysis of clinical parameters and m6A risk score level of glioblastoma (GBM) patients in the training set and validation set.

Variables Training set Validation set
Univariate analysis Univariate analysis
HR(95%CI) P-value HR(95%CI) P-value
Age group Younger vs old 0.41(0.286-0.61) 6.7e-06 1.24(0.87-1.76) 0.217
CIMP status G-CIMP vs NON 1.63(0.96- 2.78) 0.068 / /
Gender Male vs Female 1.04(0.78- 1.40) 0.764 0.91(0.63-1.32) 0.642
Subtype NE+PE vs CL+ME 1.15(0.80- 1.64) 0.437 / /
m6Arisk group Low vs High 0.48(0.34- 0.70) 8.67e-05 0.53 (0.32-0.86) 0.0103
Radiotherapy Yes vs No / / 0.51(0.26-1.02) 0.05
Chemotherapy Yes vs No / / 0.59(0.30-1.18) 0.139
IDH status Wildtype vs Mutant / / 1.45(0.83-2.53) 0.190
1p19q status Non vs Codel / / 1.20(0.48-2.97) 0.690

Bold values are statistically significant.