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. 2021 Feb 25;12:601963. doi: 10.3389/fmicb.2021.601963

Figure 3.

Figure 3

Metabolic pathway of 2-Phenylethanol (2-PE) production in Saccharomyces cerevisiae. The Ehrlich pathway (red) and phenylpyruvate pathway (the combination of red and blue) produce 2-PE. PEP, phosphoenolpyruvate; PYR, pyruvate; E4P, erythrose-4-phosphate; DAHP, 3-deoxy-D-arabinoheptulosonate; DHQ, 3-dehydroquinate; DHS, 3-dehydroshikimate; SHK, shikimate; S3P, shikimate-3-phosphate; EPSP, 5-enolpyruvyshikimate-3-phosphate; CHR, chorismite; L-Phe, L-phenylalanine; PPA, phenylpyruvate; PAAL, phenylacetaldehyde; and 2-PE, 2-phenylethanol. 1, phospho-2-dehydro-3-deoxyheptonate aldolase ARO3/4; 2, pentafunctional AROM polypeptide ARO1; 3, chorismate synthase ARO2; 4, chorismate mutase ARO7; 5, prephenate dehydratase PHA2; 6, aminotransferase ARO8/9; 7, decarboxylase ARO10; 8, dehydrogenase ADH; 9, citrate T-cell target antigen CTT1/2; 10, aconitase ACO1; 11, isocitrate dehydrogenase IDH1/2; 12, NAD-dependent glutamate dehydrogenase 2 GDH2; 13, NADP-dependent glutamate dehydrogenase 3 GDH3; 14, NADH-dependent glutamate synthase 1 GLT1; and 15, glutamate-ammonia ligase GLN1.