Table 3. Incidence of Dementia Diagnoses Among Medicare Recipients With Schizophrenia vs Recipients Without SMI by Age and Sex.
| Age, y | Cohort with schizophrenia | Cohort without SMI | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| All | Male | Female | All | Male | Female | |||||||||
| No. of patients | Incidence, per 1000 person-years (95% CI) | No. of patients | Incidence, per 1000 person-years (95% CI) | No. of patients | Incidence, per 1000 person-years (95% CI) | No. of patients | Incidence, per 1000 person-years (95% CI) | No. of patients | Incidence, per 1000 person-years (95% CI) | No. of patients | Incidence, per 1000 person-years (95% CI) | |||
| Total | New dementia diagnoses | Total | New dementia diagnoses | |||||||||||
| 66 | 41 335 | 1819 | 52.5 (50.1-54.9) | 18 435 | 52.4 (48.8-56.0) | 22 900 | 52.6 (49.3-55.8) | 2 341 437 | 9919 | 4.5 (4.4-4.6) | 956 593 | 5.2 (5.0-5.3) | 1 384 844 | 4.0 (3.9-4.1) |
| 67 | 31 977 | 1650 | 60.4 (57.5-63.4) | 13 847 | 61.2 (56.7-65.7) | 18 130 | 59.9 (56.0-63.7) | 2 359 510 | 12 282 | 5.8 (5.6-5.9) | 952 055 | 6.5 (6.3-6.7) | 1 407 455 | 5.2 (5.1-5.4) |
| 68 | 23 851 | 1334 | 66.0 (62.4-69.5) | 10 130 | 70.6 (65.0-76.3) | 13 721 | 62.6 (58.0-67.1) | 2 222 272 | 13 064 | 6.5 (6.4-6.6) | 888 113 | 7.1 (6.9-7.2) | 1 334 159 | 6.1 (5.9-6.2) |
| 69 | 17 640 | 1027 | 68.8 (64.6-73.0) | 7324 | 70.4 (63.7-77.0) | 10 316 | 67.7 (62.2-73.1) | 2 115 877 | 14 706 | 7.6 (7.5-7.7) | 841 652 | 8.2 (8.0-8.4) | 1 274 225 | 7.2 (7.1-7.4) |
| 70 | 13 008 | 807 | 74.8 (69.6-80.0) | 5278 | 74.4 (66.3-82.5) | 7730 | 75.1 (68.4-81.8) | 2 054 458 | 16 562 | 8.8 (8.6-8.9) | 814 722 | 9.1 (8.8-9.3) | 1 239 736 | 8.6 (8.4-8.8) |
| 71 | 9234 | 647 | 86.3 (79.7-93.0) | 3658 | 80.8 (70.5-91.1) | 5576 | 89.9 (81.2-98.6) | 2 000 219 | 17 968 | 9.8 (9.6-9.9) | 790 940 | 10.0 (9.8-10.2) | 1 209 279 | 9.6 (9.4-9.8) |
| 72 | 6553 | 530 | 100.2 (91.7-108.8) | 2511 | 100.9 (87.0-114.8) | 4042 | 99.8 (89.5-115.6) | 1 966 332 | 20 682 | 11.3 (11.1-11.4) | 775 256 | 11.6 (11.4-11.9) | 1 191 076 | 11.0 (10.8-11.2) |
| 73 | 4601 | 368 | 101.6 (91.2-117.9) | 1679 | 99.9 (82.8-117.0) | 2922 | 102.5 (89.5-115.6) | 1 963 967 | 23 467 | 12.8 (12.6-13.0) | 770 929 | 12.9 (12.7-13.2) | 1 193 038 | 12.7 (12.5-12.9) |
| 74 | 3141 | 250 | 104.9 (91.9-117.9) | 1090 | 112.8 (89.6-135.9) | 2051 | 100.8 (85.2-116.5) | 1 945 199 | 26 721 | 14.7 (14.5-14.9) | 758 057 | 14.9 (14.7-15.2) | 1 187 142 | 14.6 (14.4-14.8) |
| 75 | 2127 | 179 | 116.9 (99.8-134.0) | 670 | 125.3 (93.0-157.5) | 1457 | 113.4 (93.2-133.6) | 1 904 886 | 30 113 | 16.9 (16.8-17.1) | 733 735 | 17.0 (16.7-17.3) | 1 171 151 | 16.9 (16.7-17.1) |
| 76 | 1347 | 158 | 143.5 (121.1-165.9) | 392 | 118.2 (80.1-156.3) | 955 | 153.6 (126.2-180.9) | 1 876 256 | 33 429 | 19.3 (19.1-19.6) | 712 871 | 19.6 (19.2-19.9) | 1 163 385 | 19.2 (18.9-19.5) |
| 77 | 1195 | 154 | 162.3 (136.6-187.9) | 351 | 180.8 (130.2-231.4) | 844 | 155.1 (125.4-184.8) | 1 799 011 | 36 773 | 22.3 (22.0-22.5) | 672 315 | 22.6 (22.2-23.0) | 1 126 696 | 22.1 (21.8-22.4) |
| 78 | 1027 | 124 | 151.6 (124.9-178.3) | 290 | 120.7 (76.0-165.4) | 737 | 163.8 (131.1-196.6) | 1 723 060 | 39 770 | 25.2 (24.9-25.4) | 632 054 | 25.2 (24.8-25.6) | 1 091 006 | 25.2 (24.9-25.5) |
| 79 | 905 | 114 | 159.0 (129.8-188.2) | 250 | 205.0 (142.2-267.8) | 655 | 141.2 (10.8.8-173.6) | 1 639 281 | 42 677 | 28.5 (28.3-28.8) | 589 900 | 28.5 (28.1-29.0) | 1 049 381 | 28.6 (28.2-28.9) |
| 80 | 798 | 136 | 216.2 (179.9-252.6) | 219 | 241.2 (167.4-315.0) | 579 | 207.0 (165.4-248.6) | 1 552 326 | 45 581 | 32.3 (32.0-32.6) | 546 595 | 32.0 (31.5-32.5) | 1 005 731 | 32.4 (32.0-32.8) |
| 81 | 683 | 86 | 161.7 (127.5-195.8) | 176 | 175.2 (105.1-245.3) | 507 | 157.4 (118.2-196.5) | 1 464 288 | 48 681 | 36.5 (36.2-36.9) | 502 695 | 36.1 (35.6-36.7) | 961 593 | 36.7 (36.3-37.1) |
| 82 | 610 | 93 | 196.2 (156.3-236.1) | 146 | 220.2 (132.1-308.3) | 464 | 189.0 (144.4-233.6) | 1 371 758 | 51 388 | 41.3 (41.0-41.7) | 457 688 | 40.7 (40.0-41.3) | 914 070 | 41.6 (41.2-42.1) |
| 83 | 540 | 104 | 254.9 (205.9-303.9) | 125 | 247.3 (146.2-348.4) | 415 | 257.1 (201.1-313.1) | 1 273 856 | 53 614 | 46.6 (46.2-47.0) | 411 327 | 45.3 (44.7-46.0) | 862 529 | 47.1 (46.6-47.6) |
| 84 | 429 | 68 | 204.2 (155.7-252.7) | 94 | 114.3 (35.1-193.5) | 335 | 228.1 (170.4-285.9) | 1 178 492 | 55 594 | 52.2 (51.8-52.7) | 368 864 | 51.4 (50.6-52.2) | 809 628 | 52.6 (52.1-53.1) |
| 85 | 360 | 49 | 173.8 (125.1-222.4) | 76 | 133.3 (40.9-225.7) | 284 | 183.9 (127.6-240.1) | 1 080 843 | 56 635 | 58.4 (57.9-58.9) | 328 644 | 57.6 (56.7-58.5) | 752 199 | 58.7 (58.1-59.3) |
| 86 | 328 | 48 | 191.2 (137.1-245.3) | 74 | 211.5 (86.5-336.5) | 254 | 185.9 (126.0-245.8) | 975 933 | 56 321 | 64.7 (64.1-65.2) | 287 628 | 62.6 (61.6-63.6) | 688 305 | 65.5 (64.9-66.1) |
| 87 | 274 | 45 | 206.4 (146.1-266.7) | 54 | 190.5 (58.5-322.5) | 220 | 210.2 (142.5-278.0) | 873 552 | 56 454 | 73.0 (72.4-73.6) | 248 710 | 71.7 (70.6-72.9) | 624 842 | 73.5 (72.8-74.2) |
| 88 | 237 | 52 | 292.1 (212.7-371.5) | 48 | 375.0 (162.8-587.2) | 189 | 274.0 (189.1-358.9) | 764 724 | 53 975 | 80.2 (79.6-80.9) | 209 994 | 80.1 (78.8-81.4) | 554 730 | 80.3 (79.5-81.1) |
| 89 | 186 | 44 | 312.1 (219.9-404.3) | 32 | 333.3 (102.3-564.3) | 154 | 310.3 (209.0-411.7) | 654 331 | 50 279 | 88.1 (87.4-88.9) | 172 722 | 85.6 (84.1-87.1) | 481 609 | 89.0 (88.1-89.9) |
| 90 | 145 | 31 | 292.5 (189.5-395.4) | 24 | 375.0 (74.9-675.1) | 121 | 277.8 (168.9-386.7) | 551 617 | 45 206 | 94.7 (93.9-95.6) | 139 669 | 92.0 (90.2-93.7) | 411 948 | 95.7 (94.7-96.7) |
| 91 | 108 | 26 | 333.3 (205.2-461.5) | 11 | 333.3 (0-710.5) | 97 | 333.3 (197.1-469.6) | 456 476 | 41 073 | 104.9 (103.9-105.9) | 111 102 | 103.0 (101.0-115.1) | 345 374 | 105.5 (104.4-106.7) |
| 92 | 85 | 13 | NRa | NRa | 142.9 (0-422.9) | 75 | 206.9 (89.8-324.0) | 369 869 | 36 478 | 116.2 (115.0-117.4) | 86 466 | 112.8 (110.3-115.2) | 283 403 | 117.2 (115.9-118.6) |
| 93 | 75 | 21 | NRa | NRa | 400.0 (0-954.4) | 67 | 413.0 (227.3-598.8) | 293 622 | 31 195 | 126.7 (125.3-128.1) | 65 991 | 123.8 (120.8-126.8) | 227 631 | 127.5 (125.9-129.1) |
| 94 | 53 | 13 | NRa | NRa | 200.0 (0-592.0) | 47 | 363.6 (157.9-569.4) | 227 275 | 25 773 | 136.7 (135.1-138.4) | 48 901 | 134.3 (130.7-137.9) | 178 374 | 137.4 (135.5-139.3) |
| ≥95 | 99 | 24 | 338.0 (202.8-473.3) | 25 | 200.0 (4.0-396.0) | 74 | 392.2 (220.3-564.0) | 563 080 | 73 252 | 162.9 (161.8-164.1) | 104 099 | 155.3 (152.6-158.0) | 458 981 | 164.6 (163.3-165.9) |
Abbreviations: NR, not reported; SMI, serious mental illness.
a
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