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. 2020 Nov 11;320(2):R149–R161. doi: 10.1152/ajpregu.00234.2020

Figure 3.

Figure 3.

Uterine artery resistance index (UARI) at gestation day 20 (G20) in reduced uterine perfusion pressure (RUPP) and Sham-operated dams in response to vehicle or a soluble guanylate cyclase (sGC) stimulator (Riociguat 10 mg/kg/day). A: representative UARI images. The blue arrow indicates the point of peak systolic velocity (ESV), and the yellow arrow indicates the point of end-diastolic velocity (EDV). B: UARI was calculated using the following formula: UARI = (PSV − EDV)/PSV. n = 8 Sham rats, n = 9 RUPP rats, n = 9 sGC-treated Sham rats, n = 8 sGC-treated RUPP rats. Each scatter plot represents means ± SD. Two-way ANOVA with uncorrected Fisher’s least significant difference post hoc analysis was used for pairwise comparison. *P < 0.05 denotes significant difference between groups.