Table 1.
Demographics and characteristics of patients with gastroparesis in the CPRD
| Study variable | Patients with gastroparesis |
| (n=1135) | |
| Sex, n (%) | |
| Female | 723 (63.7) |
| Male | 412 (36.3) |
| Age at first gastroparesis diagnosis, years | |
| Mean (SD) | 50.6 (20.1) |
| Ethnicity, n (%) | |
| n | 608 |
| White | 517 (85.0) |
| Asian | 74 (12.2) |
| Other | 17 (2.8) |
| Body weight, kg | |
| n | 709 |
| Mean (SD) | 74.2 (20.8) |
| BMI, kg/m2 | |
| n | 687 |
| Mean (SD) | 27.2 (8.1) |
| Median (Q1, Q3) | 26.5 (22.3, 31.0) |
| BMI category, n (%) | |
| n | 687 |
| Underweight (<18.5 kg/m2) | 51 (7.4) |
| Normal (18.5–<25 kg/m2) | 226 (32.9) |
| Overweight (25–<30 kg/m2) | 194 (28.2) |
| Class I obesity (30–<35 kg/m2) | 139 (20.2) |
| Class II obesity (35–<40 kg/m2) | 44 (6.4) |
| Class III obesity (≥40 kg/m2) | 33 (4.8) |
| HbA1c, mmol/mol | |
| n | 357 |
| Mean (SD) | 66.5 (25.1) |
| Alcohol use, n (%) | |
| Never | 177 (15.6) |
| Former | 136 (12.0) |
| Current | 582 (51.3) |
| Unknown | 240 (21.1) |
| Smoking status, n (%) | |
| Never | 324 (28.5) |
| Former | 453 (39.9) |
| Current | 214 (18.9) |
| Unknown | 144 (12.7) |
| Duration of CPRD registration before index date, years | |
| Mean (SD) | 9.1 (5.8) |
| Duration of follow-up post-index date, years | |
| Mean (SD) | 4.7 (3.4) |
| Charlson Comorbidity Index | |
| Mean (SD) | 1.8 (2.0) |
| Median (Q1, Q3) | 1.0 (0.0, 3.0) |
| Charlson Comorbidity Index category | |
| 0 | 378 (33.3) |
| 1–2 | 439 (38.7) |
| 3–4 | 204 (18.0) |
| >=5 | 114 (10.0) |
| Comorbidities, n (%) | |
| Cancer | 109 (9.6) |
| Cerebrovascular disease | 75 (6.6) |
| Congestive heart failure | 37 (3.3) |
| Chronic pulmonary disease | 309 (27.2) |
| Dementia | 13 (1.1) |
| Diabetes with complications | 308 (27.1) |
| Diabetes | 118 (10.4) |
| Hemiplegia or paraplegia | 13 (1.1) |
| HIV/AIDS | 3 (0.3) |
| Myocardial infarction | 50 (4.4) |
| Mild liver disease | 21 (1.9) |
| Moderate or severe liver disease | 6 (0.5) |
| Metastatic solid tumour | 7 (0.6) |
| Peptic ulcer disease | 92 (8.1) |
| Peripheral vascular disease | 60 (5.3) |
| Renal disease | 147 (13.0) |
| Rheumatic disease | 69 (6.1) |
AIDS, acquired immunodeficiency syndrome; BMI, body mass index; CPRD, Clinical Practice Research Datalink; HbA1c, glycated haemoglobin; HIV, human immunodeficiency virus; SD, standard deviation.