. 2020 Nov 13;151(3):491–502. doi: 10.1093/jn/nxaa312

TABLE 2.

Fecal bacterial taxa abundances at the genus level at baseline and change after 12 wk of intervention that were found to be significantly different within and/or between the WGW and RW group in middle-aged overweight and obese adults¹

	RW group		WGW group		Within RW		Within WGW		Group comparison
Bacteria	Baseline relative abundance, %	Δ Relative abundance after 12 wk, %	Baseline relative abundance, %	Δ Relative abundance after 12 wk, %	P value	FDR P value	P value	FDR P value	P value	FDR P value
f_Ruminococcaceae; g_Ruminiclostridium_9	0.20 ± 0.23	−0.081 ± 0.17	0.065 ± 0.11	0.054 ± 0.14	0.07	NS²	0.07	NS	0.003	NS
f_Ruminococcaceae; g_Ruminococcaceae_NK4A214_group	0.64 ± 1.3	−0.15 ± 0.49	0.37 ± 0.56	0.17 ± 0.83	0.12	NS	0.11	NS	0.036	NS
f_Lachnospiraceae; g_Lachnospiraceae_UCG-008	0.00 ± 0.00	0.043 ± 0.10	0.10 ± 0.12	−0.023 ± 0.083	0.18	NS	0.19	NS	0.044	NS
f_Ruminococcaceae; g_Ruminococcaceae_UCG-014	1.6 ± 2.1	−0.31 ± 0.78	2.2 ± 4.6	0.51 ± 4.2	0.12	NS	0.13	NS	0.033	NS
f_Lachnospiraceae; g_Dorea	1.7 ± 1.1	−0.72 ± 0.91	1.6 ± 0.81	−0.018 ± 0.99	0.005	NS	0.61	NS	0.055	NS
f_Tannerellaceae; g_Parabacteroides	0.37 ± 0.30	0.60 ± 1.42	0.45 ± 0.41	0.35 ± 0.97	0.007	NS	0.18	NS	0.32	NS
f_Lachnospiraceae; g_[Eubacterium]_ventriosum_group	0.17 ± 0.23	−0.14 ± 0.24	0.14 ± 0.14	−0.050 ± 0.15	0.044	NS	0.71	NS	0.18	NS
f_Peptostreptococcaceae_g_unknown	1.2 ± 2.8	−0.64 ± 1.5	0.56 ± 0.71	−0.23 ± 0.69	0.024	NS	0.18	NS	0.57	NS
f_Ruminococcaceae; g_Ruminococcus_2	1.4 ± 1.3	−0.24 ± 1.5	2.1 ± 1.8	−1.1 ± 2.1	0.11	NS	0.024	NS	0.44	NS
f_Ruminococcaceae; g_Subdoligranulum	6.8 ± 4.7	−1.7 ± 4.6	6.1 ± 5.3	−1.8 ± 3.7	0.10	NS	0.024	NS	0.89	NS
f_Burkholderiaceae; g_Sutterella	0.27 ± 0.44	0.085 ± 0.45	0.35 ± 0.92	0.30 ± 0.49	0.31	NS	0.010	NS	0.46	NS
f_Ruminococcaceae; g_Ruminococcaceae_UCG-005	1.1 ± 1.1	0.38 ± 1.5	0.91 ± 1.1	0.21 ± 1.0	0.75	NS	0.042	NS	0.47	NS

Values are presented as group means ± SD, n = 16 (RW) or n = 21 (WGW). FDR, false discovery rate; RW, refined wheat; WGW, whole grain wheat; Δ, differential change over time.

²NS, nonsignificant: P value > 0.05.