Table 4. AutoDock Vina (S_ij) and Modified* (S_ij′) Scores (kcal mol^–1) for the Four Ligands from the Natural Extracts of the Species M. taxifolia and for Three Known Ligands against Both Nonstructural Proteins NS3-Helicase and NS5-RNS Polymerase of the Zika and Dengue Virus^a.

	receptor (ZIK)				receptor (DEN)
	NS3-helicase		NS5-RNA polym.		NS3-helicase		NS5-RNA polym.		NS5-RNA polym.
Ligand	Sij	Sij′	Sij	Sij′	Sij	Sij′	Sij	Sij′	Sij	Sij′	μi	σi
5DP	–8.17	–1.57	–6.20	0.68	–5.90	1.02	–6.80	–0.01	–6.90	–0.12	–6.794	0.874
5HH	–8.10	–1.68	–6.15	0.31	–5.60	0.87	–5.90	0.56	–6.50	–0.05	–6.450	0.980
M3OR	–9.60	–1.59	–7.78	0.36	–7.10	1.09	–7.80	0.34	–8.30	–0.20	–8.116	0.933
M3RG	–7.81	0.02	–7.97	–0.46	–7.50	0.93	–7.50	0.93	–8.30	–1.43	–7.816	0.338
LNY	–7.95	–1.37	–6.72	0.23	–5.80	1.42	–6.90	–0.01	–7.10	–0.27	–6.894	0.772
68T	–7.44	0.19	–6.84	0.92	–6.80	0.97	–8.50	–1.10	–8.40	–0.98	–7.596	0.821
AMP	–9.02	–1.48	–6.37	0.97	–8.00	–0.54	–6.70	0.66	–7.00	0.39	–7.418	1.083

^aμ_i and σ_i are the average binding values used for the calculation of S_ij’ (eqs 2–4).