Table 11.
Noninfectious toxicities during treatment
| Toxicity (CTCAE grading v4.03) | n (%) |
|---|---|
| Cortical venous thrombosis (grade 4) | 22 (6.3) |
| Bacterial infections (episodes) (grade 2-5) | 91 |
| Fungal infections (episodes) (grade 2-5) | 104 (29.7) |
| Pancreatitis (grade 3-5) | 17 (4.8) |
| Hyperglycemia (grade 3-5) | 9 (2.5) |
| Avascular necrosis (grade 2-5) | 4 (1.1) |
| PRES (grade 4) | 5 (1.4) |
| Seizures (grade 2-5) | 45 (12.8)* |
Possible and probable fungal pneumonia was defined as per revised EORTC and MSGERC definitions.38
CTCAE, Common Terminology Criteria for Adverse Events.
*
Thirteen patients had CVT.