Table 2.
Imatinib side effects (N = 158)
| Variable | No. of patients, n (%) |
|---|---|
| Reported side effects | 132 (83.5) |
| Types of side effects | |
| Cytopenia | 94 (59.5) |
| GI side effects | 42 (26.6) |
| Musculoskeletal pain | 23 (14.6) |
| Hypopigmentation | 22 (13.9) |
| Edema | 17 (10.8) |
| Skin rash | 12 (7.6) |
| Weight gain | 6 (3.8) |
| Hemorrhage | 4 (2.5) |
| Fever | 1 (0.6) |
| Imatinib interruption due to cytopenia | 93 (58.9) |
| Frequency of interruption | |
| 1 time | 35 (22.2) |
| 2 times | 17 (10.8) |
| ≥3 times | 41 (26.0) |
| Observed cytopenia at study recruitment | |
| Neutropenia, all grades | 65 (41.1) |
| Grade 1 | 35 (22.2) |
| Grade 2 | 17 (10.7) |
| Grade 3 | 11 (6.9) |
| Grade 4 | 2 (1.3) |
| Thrombocytopenia, all grades | 34 (21.5) |
| Grade 1 | 25 (15.8) |
| Grade 2 | 4 (2.5) |
| Grade 3 | 2 (1.3) |
| Grade 4 | 3 (1.9) |
| Anemia, all grades | 103 (65.1) |
| Grade 1 | 67 (42.4) |
| Grade 2 | 28 (17.7) |
| Grade 3 | 8 (5.0) |
Data are number of patients (percentage of total study group).