Table 4.

Summary of Lobene scores at 8 Weeks of the patients who completed the study

Variables	Test toothpaste	Control toothpaste	Difference between groups (%)	P Between groups*
Lobene stain area score
Adjusted mean (SE)	0.83 (0.05)	1.13 (0.05)	26.55%	< 0.001
95% Confidence interval	(0.72, 0.93)	(1.02, 1.23)
Change from baseline (%)	49.08%	28.93%
P versus baseline†	< 0.001	< 0.001
Lobene stain intensity score
Adjusted mean (SE)	0.99 (0.06)	1.32 (0.06)	25%	< 0.001
95% Confidence interval	(0.87, 1.12)	(1.20, 1.44)
Change from baseline (%)	41.42%	23.26%
P versus baseline†	< 0.001	< 0.001
Lobene stain composite score
Adjusted mean (SE)	1.45 (0.13)	2.50 (0.13)	42%	< 0.001
95% Confidence interval	(1.19, 1.72)	(2.24, 2.76)
Change from baseline (%)	60.81%	32.8%
P versus baseline†	< 0.001	< 0.001

*ANCOVA

^†Paired t test