Figure 1.

Putative phosphorylation of the RB C-terminus.A, the open reading frame for RB is shown depicting known CDK phosphorylation sites (top) and uncharacterized, non-CDK phosphorylation sites in RBC (bottom). RB N-terminal domain (RBN), A and B halves of the pocket domain, and RB C-terminal domain (RBC) are shown. B, chart displaying potential phosphorylation sites in the amino acid 825 to 860 region of the RB C-terminus. Putative phosphorylation sites identified in publicly available phosphoproteomic studies are shaded in blue and the relevant data sources are indicated. CST, Cell Signaling Technologies data set.