Skip to main content
. 2020 Dec 25;296:100221. doi: 10.1074/jbc.RA120.016297

Figure 1.

Figure 1

Catalytic cycle of flavin-containing monooxygenases.A, binding of NADPH and subsequent reduction of the flavin. B, reaction with molecular oxygen and C(4α)-hydroperoxyflavin intermediate formation. C, uncoupling: release of hydrogen peroxide and NADP+. D, oxygen atom transfer to a substrate. E, release of water. F, release of NADP+.