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. 2020 Dec 18;296:100172. doi: 10.1074/jbc.RA120.016557

Table 2.

Low doses of compound mixtures are more active repellents than single ones

Compound μL equivalent of each compound per cm2 nmole of each compound per cm2 Mean % repellency DEET Pr(<[t]) Single compound Pr(<[t])
DEET 0.01 52 96.7 ± 2.6
CRV 0.01 65 67.8 ± 9.0 6.9E-16
CA 0.01 65 63.2 ± 11.8 1.3E-14
OCT 0.01 70 13.8 ± 12.8 8.6E-25
CRV+CA 0.005 32.5 + 32.5 93.1 ± 6.8 0.02971 CRV CA
1.8E-05 3.7E-05
CRV+OCT 0.005 32.5 + 35 84.2 ± 6.6 1.3E-09 CRV OCT
0.00087 3.9E-09
CA+OCT 0.005 32.5 + 35 76.5 ± 6.9 8.0E-14 CA OCT
0.02423 8.3E-08
CRV+CA+OCT 0.0033 21.7 + 21.7 + 23.3 91.1 ± 5.2 0.00019 CRV CA OCT
4.3E-05 9.6E-05 4.5E-09

All tests were carried out over a period of 5 min. Dichloromethane was used as a control and the numbers of landings for the experiments involving compound equivalent doses of 0.2, 0.04, and 0.01 μl/cm2 are presented in Table S2. Statistically significant differences, between antagonists and DEET control, are those with Pr(<[0.05]).

CA, cumin alcohol; CRV, carvacrol; DEET, N,N-diethyl-3-methylbenzamide; OCT, (2E,4E)-2,4-octadienal.