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Heme does not affect inhibition of phenazine production by CP. Average (A) PYO and (B) PCA concentrations in supernatants from Pseudomonas aeruginosa PA14 cultures grown in CDM in the absence or presence of CP-Ser (10 μM) and heme (5 μM) (N = 4, ∗p < 0.05, ∗∗p < 0.01). CDM, chemically defined medium; CP, calprotectin; PCA, phenazine-1-carboxylate; PYO, pyocyanin.
