Figure 5.

Ferritin is increased in RPE of patient diagnosed with recessive Stargardt disease (STGD1). Fluorescence micrographs of human retinal sections immunostained with mouse anti-ferritin-L. Ferritin, purple; green, RPE lipofuscin autofluorescence. A, healthy control eye, no primary antibody. B, healthy control, anti-Ferritin L. C, STGD1 control: no primary antibody. D, STGD1, anti-Ferritin-L immunostaining. Note that the neural retina was detached from the RPE during tissue processing. Thus the RPE-region of the image was moved closer to the neural retina using Photoshop. Green, RPE lipofuscin autofluorescence.