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. 2019 Jan 29;16(3):601–620. doi: 10.1111/iwj.13069

Table 5.

Microbial indicators used to diagnose infected leg ulcers

Microbial indicators Authors, year Total leg ulcers Total studies
Culture positive Alcaraz & Kelly71; Danielsen et al49; Flock et al67; Imbernon et al93; Imbernon‐Moya et al91; Isbary et al17; Isbary et al16; Lei et al20; Madhusudhan21; Lisle60; Gerry et al92; Graham59; Nagoba et al68; Martin et al70; Rossi & Wertzberger61; Sari et al62; Thai et al63; Tudor50; Salavastru et al66 617 20
Bacterial load >105 CPU/g of tissue Bhat et al34; Gardner et al32; Gardner et al52; Peral et al75; Lantis & Gendics22; Raad et al81 127 6
Bacterial load >105 CPU/mL fluid or/cm2 fluid Daróczy19; Kordestani et al18; Sibbald et al38; Woo et al36 141 4
β‐haemolytic Streptococcus at any levels Gardner et al32; Gardner et al52 14 2
Bacterial load >106 CPU/g of tissue Sibbald et al40 20 1
If beta‐haemolytic streptococcus present then ≥103 CFU/mL Kordestani et al18 20 1

CFU, colony‐forming units.