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. 2020 Aug 23;17(6):1909–1923. doi: 10.1111/iwj.13481

TABLE 2.

Summary of the use of artificial intelligence for wound assessment or monitoring in diabetic foot ulcer (DFU)

Author (year) Type of AI n Wound Type Clinical Use Measurement Accuracy Remote Assessment Capabilities Challenges
Goyal et al (2020) 11

Faster R‐CNN with InceptionResNet V2

BayesNet

Random forest

InceptionV3

ResNet

1459 DFU Recognition of ischemia and infection in monitoring of DFU

Average accuracy of all models:

Ischemia: 83.3%

Infection: 65.8%

Eventually transit into a remote DFU diagnosis system, but challenges need to be resolved

Substantial datasets required for good accuracy

Images provided for assessment are non‐standardised (type of camera models, devices, poses and illumination)

Wang et al (2019) 12

Associative hierarchal random field (AHRF) model

Conditional random field (CRF) model

100 Any foot ulcer Accurately determining boundaries of ulcer images acquired under various image acquisition conditions

Wound recognition specificity:

AHRF model – 95.5% to 99.2%

CRF model 1 (conditional random field) – 89.8% to 92.7%

CRF model 2 –91.1% to 98.4%

Wound recognition sensitivity

AHRF – 76.9% to 84.4%

CRF model 1 – 61.8% to 67.4%

CRF model 2 – 70.3% to 76.7%

Need to expand diversity of database of real wound images, with possibility of expanding into deep learning in the future
Ohura et al (2019) 14

Convolutional Neural Networks (CNNs):

SegNet

LinkNet

U‐Net

U‐Net_VGG16

440 Chronic wounds Construct a good wound segmentation model using CNN

SegNet:

AUC 0.994, sensitivity 0.909, Specificity 0.982, accuracy 0.976

LinkNet:

AUC 0.987, sensitivity 0.989, specificity 0.989, accuracy 0.972

U‐Net:

AUC 0.997, sensitivity 0.993, specificity 0.993, accuracy 0.988

U‐Net_VGG16

AUC 0.998, sensitivity 0.992, specificity 0.992, accuracy 0.989 – highest accuracy

May not be applicable to wound assessment and segmentation of other races (study was conducted in a Japanese population)
Wang et al (2017) 16 Two‐stage support vector machine (SVM) with conditional random field (CRF) image processing 100 DFU Create an automated wound detection method to determine wound area on a smartphone‐based system

Two‐stage SVM + CRF technique:

Sensitivity – 73.3%

Specificity – 94.6%

Computation time – 20.5 s

Need to enhance wound image database

Need to recruit more clinicians to delineate wound boundaries to minimise variability