TABLE 1.
Patient characteristics
| Patient no. | Patient baseline characteristics | Relevant concomitant diseases | Immunosuppressive medication | Previous local treatments | |
|---|---|---|---|---|---|
| Age (in years) | Gender | ||||
| 1 | 62 | M | PAD, sepsis, LV heart failure, HTN, AS, lymphedema lower legs, ARF | Wound antiseptics, antimicrobial wound dressings | |
| 2 | 47 | M | PG, RA, high‐grade left IAD, HTN, nicotine abuse | Infliximab, methotrexate, abatacept, prednisolone | Wound antiseptic, antimicrobial wound dressings |
| 3 | 50 | F | MCTD (sharp syndrome), PF, HTN, AFL | Prednisolone | Antimicrobial wound dressing, wound disinfection, surgical debridement, STSG |
| 4 | 62 | F | CV | Rituximab, mycophenolate mofetil, prednisolone | Steroids |
| 5 | 66 | F | PG, CVI, CHD, IC, HTN, ARF, lymphedema | Mycophenolate mofetil, prednisolone | Wound antiseptics, antimicrobial wound dressing, topical steroids |
| 6 | 57 | M | VTE (DVT), CML, HTN | Mycophenolate mofetil, ciclosporine | Surgical debridement, negative pressure therapy, STSG |
| 7 | 62 | M | CVI, DM, HTN, obesity | Surgical debridement, negative pressure therapy, wound antiseptic, antimicrobial wound dressing, topical steroids, compression therapy, STSG | |
| 8 | 79 | F | CVI, PCV, HTN | Hydroxycarbamide | Surgical and biomechanical debridement, negative pressure therapy, wound antiseptic, silicone wound dressing, zinc |
| 9 | 74 | F | PAD, varicosis, PNP, lymphedema, HTN, CRF | Surgical and biomechanical debridement, wound antiseptics, polyurethane wound dressings, compression therapy | |
| 10 | 77 | M | PAD (Stage I), CHD, HTN | Wound dressings | |
| 11 | 35 | M | VTE (SVT), lipedema (Stage III), lymphedema (Stage III), obesity | Antimicrobial wound dressings, wound desinfection, physiotherapy, lymphatic drainage | |
| 12 | 39 | M | PTS, NF, lower leg phlegmon | Compression therapy, surgical debridement, negative pressure therapy, STSG | |
| 13 | 64 | F | Bullous erysipelas, RA, HTN, CRF, obesity | Methotrexate | Antimicrobial wound dressings, wound desinfection, compression therapy, topical steroids |
| 14 | 64 | M | PAD (Stage II), CHD | Surgical debridement, STSG, antimicrobial wound dressing, compression therapy | |
| 15 | 55 | F | PAD (Stage IV), DM, HTN, CHD, obesity, cardiac valve replacement, left fore foot amputation | Wound antiseptics, topical steroids | |
| 16 | 78 | F | CVI, HTN, heart failure, CRF, obesity | Wound antiseptics, antibiotics, antimicrobial wound dressings, compression therapy, topical steroids | |
Abbreviations: AFL, atrial flutter; ARF, acute renal failure; AS, ankylosing spondylitis; B, both; CHD, chronic heart disease; CV, cryoglobulinemic vasculitis; CVI, chronic venous insufficiency; DM, diabetes mellitus; F, female; HTN, hypertension; IAD, iliac artery disease; IC, ischemic cardiomyopathy; L, left; M, male; MCTD, mixed connective tissue disease; NF, necrotizing fasciitis; PAD, peripheral artery disease; PCV, polycythemia vera; PF, pulmonary fibrosis; PG, pyoderma gangrenosum; PNP, polyneuropathy; R, right; RA, rheumatoid arthritis; STSG, split‐thickness skin graft; SVT, superficial vein thrombosis.