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HDL NPs induce ferroptosis in B cell lymphoma cells.A and B. Flow cytometric analysis of C11-BODIPY fluorescence in Ramos (A) and SUDHL4 (B) cells treated with HDL NPs (50 nM) over time. ∗p < 0.05 vs. 0 h. C and D. Cell viability (MTS) assays for Ramos (C) and SUDHL4 (D) cells treated with HDL NPs, ferrostatin-1 (1 μM), and/or DFO (1 μM) for 72 h. ∗p < 0.05 vs HDL NPs. DFO, deferoxamine; HDL NPs, high-density lipoprotein–like nanoparticles.
