Figure 6.

BCMUT and G22 expression cannot compensate for loss of BC200 expression.A, polysome analysis by sucrose density gradient centrifugation of cell lysates 48 h following transfection of a nontargeting control GapmeR (black) as compared with a BC200 targeting GapmeR (red) in cells stably expressing a GFP reporter plasmid. B, as in (A), with cells stably expressing a GFP reporter plasmid with a BC200 expression cassette (red). C, as in (A) with cells stably expressing a GFP reporter plasmid with a BCMUT expression cassette (red). D, as in (A) with cells stably expressing a GFP reporter plasmid with a G22 expression cassette (red).