Table 1.

Ligand/growth factor genes showing increased expression in NF2-null AC and MN cells

Gene ID	Protein name	NF2(−) ACs versus NF2(+) ACsa		Ben-Men-1 versus NF2(+) ACsb
		log2FC	p-valuec	log2FC	p-valuec
NRG1	Neuregulin/heregulin	4.47	6.36 × 10−6	6.28	1.45 × 10−8
HBEGF	Heparin-binding EGF-like growth factor	3.00	2.00 × 10−4	6.76	8.33 × 10−11
APLN	Apelin	2.42	1.61 × 10−2	5.88	1.84 × 10−10
TGFA	Transforming growth factor, alpha	1.89	5.62 × 10−2	3.26	4.67 × 10−6

AC, arachnoid cell; MN, meningioma.

^aData from genetically matched (isogenic) NF2(−) versus NF2(+) AC lines is summarized from previous report (21).

^bGenetically unmatched lines.

^cp-value is Bonferroni adjusted; log2FC, log2 fold change.