Figure 6.

A, relative percentage of the six most abundant lipid categories identified in gastrocnemius. The lipid extract of the gastrocnemius excised from LDLR KO male mice fed either a normal (NS; n = 7) or a low-sodium diet (LS; n =7) was subjected to a global lipidomic analysis performed with high-resolution mass spectrometry,ultra-high-performance liquid chromatography coupled to mass spectrometry coupled to ESI-Q-TOF-MS. Values expressed as average ± standard deviation were compared by the Mann–Whitney test. B, PC:PE ratio. CL, cardiolipins; PC, phosphatidylcholine; PE, phosphatidylethanolamine; PI, phosphatidylinositol; pPC, plasmenyl diacylphosphatidylcholine; pPE, plasmenyl phosphattidylethanolamine. Values expressed as median (interquartile range) were compared by the Mann–Whitney test. C, total lipid mass of DG, TG, Cer and SM in the gastrocnemius. Values expressed as median (interquartile range) were compared by the Mann–Whitney test. Cer, ceramides; DG, diacylglycerol; SM, sphingomyelin; TG, triacylglycerol.