Table 5.
Pathological characteristics of the 8 SAABMR cases with follow-up biopsy
| Case | Histological change of the Banff score by LM (diagnosis/follow) |
Histological change by EM (diagnosis/follow) |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| g (score) | ptc (score) | C4d (score) | ct (score) | ci (score) | cg by LM (score) | endothelial swelling | Subendothelial electron-lucent widening | early GBM duplication | cg by EM (score) | PTCBM multilayering | |
| 1 | 1/0 | 0/0 | 3/3 | 0/2 | 0/2 | 0/0 | −/− | −/− | −/− | 0/0 | Partially/partially |
| 2 | 1/1 | 3/2 | 3/3 | 0/1 | 0/1 | 0/0 | +/− | −/+ | −/+ | 0/1a | Partially/circular |
| 3 | 1/1 | 3/0 | 1/3 | 1/0 | 0/0 | 0/0 | +/− | −/+ | −/+ | 0/1a | Partially/partially |
| 4 | 1/2 | 2/3 | 1/3 | 1/1 | 0/1 | 0/0 | +/+ | +/− | +/− | 1a/0 | Partially/circular |
| 5 | 1/1 | 0/0 | 3/2 | 0/1 | 0/0 | 0/0 | +/+ | +/− | +/− | 1a/0 | Partially/partially |
| 6 | 2/2 | 3/3 | 2/1 | 1/1 | 1/1 | 0/0 | −/− | −/+ | −/+ | 0/1a | Partially/circular |
| 7 | 2/1 | 3/3 | 3/2 | 0/0 | 0/0 | 0/0 | +/− | +/+ | +/+ | 1a/1a | Partially/circular |
| 8 | 1/1 | 3/0 | 0/0 | 1/1 | 1/0 | 0/0 | −/− | −/+ | −/+ | 0/1a | Partially/partially |
SAABMR, subclinical acute/active antibody-mediated rejection; LM, light microscopy; EM, electron microscopy; Diagnosis, at the diagnosis of SAABMR; Follow, at the follow-up biopsy; GBM, glomerular basement membrane; PTCBM, peritubular capillary basement membrane; Partially, ≥4 layers of partially lesion; Circular, ≥4 layers of circular lesion.