Table 2.
Relationship between interesting factors and SSI after operative treatment of open fracture
| Variables | SSI (n = 501, 18.6%) | No SSI (n = 2191, 81.4%) | P value |
|---|---|---|---|
| Age > 40 (years) | 268 (53.5) | 1052 (48.0) | .011a |
| Fracture type (Gustilo‐Anderson III) | 126 (25.1) | 499 (22.8) | .000a |
| Cigarette consumption | 123 (24.6) | 400 (18.3) | .109 |
| Injured site (lower extremity) | 148 (29.5) | 663 (30.3) | .378 |
| Gender (male) | 392 (78.2) | 1635 (74.6) | .332 |
| Surgeon experience (attending) | 271 (54.1) | 997 (45.5) | .005a |
| BMI < 23 kg/m2 | 189 (37.7) | 1041 (47.5) | .200 |
| Diabetes mellitus | 28 (5.6) | 148 (6.8) | .375 |
| Hypertension | 70 (14.0) | 266 (12.1) | .306 |
| Anaemia | 3 (0.6) | 4 (0.2) | .299 |
| Length of hospital stay (>32d) | 50 (10.0) | 286 (13.1) | .013a |
| Surgical duration (>122 minutes) | 118 (23.6) | 579 (26.4) | .037 |
| Anaesthesia time (>130 minutes) | 193 (38.5) | 975 (44.5) | .010 |
| Intraoperative blood loss (320 mL) | 31 (6.2) | 171 (7.8) | .170 |
| ASA score (III‐IV) | 32 (6.4) | 151 (6.9) | .063 |
| Intraoperative body temperature (<36.4°C) | 319 (63.7) | 1570 (71.7) | .002a |
| Cleanliness of operating room | .973 | ||
| Drainage usage | 131 (26.1) | 540 (24.6) | .182 |
| Erythrocyte count (RBC < 3.82 × 1012/L) | 78 (15.6) | 254 (11.6) | .055 |
| TP (<68.9 g/L) | 265 (52.9) | 1324 (60.4) | .003a |
| ALB (<40 g/L) | 88 (17.6) | 464 (21.2) | .852 |
| GLOB (<24.1) | 176 (35.1) | 968 (44.2) | .006a |
| Leukocyte count (WBC < 9.4 × 109/L) | 168 (33.5) | 594 (27.1) | .009a |
| HGB (<146 g/L) | 319 (63.7) | 1512 (69.0) | .721 |
| GLU (>100 mg/dL) | 224 (44.7) | 814 (37.2) | .003a |
| PLT (<288 × 109/L) | 425 (84.8) | 1728 (78.9) | .008a |
Abbreviations: ALB, albumin; ASA, American Society of Anaesthesiologists; BMI, body mass index; GLOB, globulin; GLU, blood glucose; HGB, haemoglobin; PLT, blood platelet count; RBC, red blood cell; TP, total protein; SSI, surgical site infection; WBC, white blood cell.
a
Significant variables.