Table 6.
Diagnostic performance of five categorised score
| Variables | Threshold* | Sensitivity | Specificity | Accuracy | PPV | NPV | AUC | 95% CI of AUC | Comparison (P‐value †) |
|---|---|---|---|---|---|---|---|---|---|
| DUSS | 1·5 | 56/67 (0·84) | 48/70 (0·69) | 104/137 (0·76) | 56/78 (0·72) | 48/59 (0·81) | 0·8012 | 0·7305–0·8719 | DUSS versus UT on wound depth, P = 0·009 |
| UT on infection | 3·5 | 46/67 (0·69) | 58/70 (0·83) | 104/137 (0·76) | 46/58 (0·79) | 58/79 (0·73) | 0·8065 | 0·7367–0·8763 | DUSS versus Wagner, P = 0·006 |
| UT on wound depth | 2·5 | 49/67 (0·73) | 67/70 (0·96) | 116/137 (0·85) | 49/52 (0·94) | 67/85 (0·79) | 0·8856 | 0·8343–0·9369 | DUSS versus DEPA, P = 0·006 |
| Wagner | 3·5 | 50/67 (0·75) | 66/70 (0·94) | 116/137 (0·85) | 50/54 (0·93) | 66/83 (0·8) | 0·8921 | 0·842–0·9422 | UT on infection versus DEPA, P = 0·003 |
| DEPA | 8·5 | 53/67 (0·79) | 59/70 (0·84) | 112/137 (0·82) | 53/64 (0·83) | 59/73 (0·81) | 0·8908 | 0·8375–0·9442 | UT on infection versus Wagner, P = 0·016 |
| SINBAD | 4·5 | 42/67 (0·63) | 64/70 (0·91) | 106/137 (0·77) | 42/48 (0·88) | 64/89 (0·72) | 0·8483 | 0·7857–0·9108 |
AUC, area under the curve; CI, confidence interval; DEPA, depth of the ulcer, extent of bacterial colonisation, phase of ulcer and association aetiology; DUSS, diabetic ulcer severity score; NPV, negative predictive value; PPV, positive predictive value; SINBAD, site, ischaemia, neuropathy, bacterial infection, and depth; UT, University of Texas.
*
The thresholds were computed by Youden's index.
†
The P‐values for the comparison of the pairs of AUCs were calculated by Delong's method.