Table 1.
Study/year | Country | Mean age (y) | Subjects | Intervention | Time of follow up | Outcomes | ||||
---|---|---|---|---|---|---|---|---|---|---|
Aetiology | ESWT (n) | Control (n) | ESWT | Control | ||||||
1 | Dumfarth et al32 | Austria | 69.0 | Vein harvesting wounds for coronary artery bypass graft surgery | 50 | 50 | ESWT and CWT | CWT | Postoperative 7 d | ①⑧⑫ |
2 | Moretti et al33 | Italy | 56.5 | Neuropathic DFU | 15 | 15 | ESWT and CWT | CWT | 20 wk | ①②⑧ |
3 | Wang et al26 | China (Taiwan) | 61.1 | Chronic DFU | 36 | 36 | ESWT and CWT | CWT and HBOT | 6‐14 mo | ①④⑥⑦⑧⑨ |
4 | Larking et al34 | England | 63.3 | Chronic decubitus ulceration | 4 | 5 | ESWT and CWT | CWT | 6 wk | ①②③ |
5 | Ottomann et al30 | Germany | 48.8 | Skin graft donor site wounds after the acute traumatic wounds and burns | 13 | 15 | ESWT and CWT | CWT | 12 wk after hospital discharge | ①②⑧⑪ |
6 | Wang et al31 | China (Taiwan) | 61.5 | Chronic DFU | 44 | 40 | ESWT and CWT | CWT and HBOT | 3‐18mo | ①④⑥⑦⑪ |
7 | Ottomann et al29 | Germany | 45.0 | Acute second‐degree burns | 22 | 22 | ESWT and CWT | CWT | 12wk after hospital discharge | ①②⑧⑪ |
8 | Nossair et al35 | Egypt | 55.9 | Chronic DFU | 20 | 20 | ESWT and CWT | CWT | 12 wk | ③⑪ |
9 | Omar et al36 | Egypt | 56.8 | Chronic DFU | 24 | 21 | ESWT and CWT | CWT | 20 wk | ①②③④⑪ |
10 | Jeppesen et al37 | Denmark | 66.6 | Chronic DFU | 10 | 11 | ESWT and CWT | CWT | 7 wk | ③④⑤⑥⑧⑩⑪ |
Abbreviations: CWT, conventional wound therapy; DFU, diabetic foot ulcers; ESWT, extracorporeal shock wave therapy; HBOT, hyperbaric oxygen therapy; n, number of subjects; ①wound‐healing rate; ②wound‐healing time (d); ③percentage of the wounds areas (%); ④wounds status; ⑤transcutaneous oxygen tension (TcPO2); ⑥blood flow perfusion; ⑦histopathological examination; ⑧bacteriological examination; ⑨immunohistochemical analysis; ⑩pain score; ⑪adverse effects; ⑫ASEPSIS score (additional treatment, presence of serous discharge, erythema, purulent exudate, separation of the deep tissue, isolation of bacteria, and duration of inpatient stay).