Table 1.
Demographics of patients in LFCUD and UC groups
| Total sample (n = 68) | LFCUD (n = 32) | UC (n = 36) | P‐value | |
|---|---|---|---|---|
| Age (years) | 65.7 ± 10.5 | 67.2 ± 11.5 | 64.4 ± 9.5 | 0.28 |
| Male | 76.5 (52) | 75.0 (24) | 77.8 (28) | 0.79 |
| BMI | 26.4 ± 5.6 | 25.1 ± 4.8 | 27.6 ± 6.0 | 0.07 |
| Initial wound area (cm2) | 14.6 ± 20.2 | 13.5 ± 23.3 | 15.6 ± 17.3 | 0.68 |
| Wound duration (months) (n = 76) | 14.75 ± 27.32 | 17.06 ± 36.85 | 12.57 ± 13.57 | 0.68 |
| Wound location | ||||
| Toe/toe amputation site | 16.2 (11) | 15.6 (5) | 16.7 (6) | 0.91 |
| Mid‐foot/plantar | 27.9 (19) | 31.3 (10) | 25.0 (9) | 0.57 |
| Heel | 20.6 (14) | 18.8 (6) | 22.2 (8) | 0.72 |
| Malleolar | 7.4 (5) | 9.4 (3) | 5.6 (2) | 0.66 |
| Leg | 27.9 (19) | 25.0 (8) | 30.6 (11) | 0.61 |
| Diabetes | 69.1 (47) | 71.9 (23) | 66.7 (24) | 0.64 |
| Duration diabetes (years) (n = 45) | 20.56 ± 12.30 | 22.23 ± 13.72 | 18.96 ± 10.85 | 0.38 |
| Anticoagulant medication | 64.7 (44) | 65.6 (21) | 63.9 (23) | 0.89 |
| Antibiotic medication | 64.7 (44) | 62.5 (20) | 66.7 (24) | 0.72 |
| Haemoglobin (n = 77) | 114.21 ± 18.99 | 112.2 ± 17.33 | 116.1 ± 20.47 | 0.41 |
| HbA1C | 7.61 ± 1.45 | 7.59 ± 1.24 | 7.63 ± 1.65 | 0.93 |
| Albumin (n = 70) | 31.4 ± 5.68 | 30.9 ± 6.67 | 31.84 ± 4.65 | 0.54 |
| NPWT | 36.8 (25) | 34.4 (11) | 38.9 (14) | 0.70 |
| ABPI (n = 25) | 0.92 ± 2.34 | 0.83 ± 0.19 | 1.03 ± 0.25 | 0.03* |
| Arterial insufficiency | n = 60 | n = 29 | n = 31 | |
| Pedal pulse present a | 18.3 (11) | 13.8 (4) | 22.6 (7) | 0.42 |
| Angioplasty | 55.0 (33) | 55.2 (16) | 54.8 (17) | 0.98 |
| Bypass graft | 33.3 (20) | 27.6 (8) | 38.7 (12) | 0.36 |
| Prior amputation: | ||||
| Major: (transtibial/transfemoral) | 11.7 (7) | 6.9 (2) | 16.1 (5) | 0.43 |
| Distal: (pedal/digital) | 30.0 (18) | 44.8 (13) | 16.1 (5) | 0.02** |
Abbreviations: BMI, body mass index; HbA1C, glycated haemoglobin; LFCUD, low‐frequency (22.5 kHz) contact ultrasound debridement; NPWT, receiving negative pressure wound therapy to wound; UC, usual care.
Unless otherwise stated, values are expressed as mean ± Standard Deviation, with range in parentheses, or percentage (n).
a
Pedal Pulse Palpable = Dorsalis Pedis and/or Posterior Tibial pedal pulse palpable in affected limb.
*
Statistically significant difference but partial sample only: t (23)=−2.270, P = 0.033, n = 25.
**
Statistically significant difference: x 2 (1) = 5.88, P = 0.015.