| Porous resorbable matrix of about 2 mm thickness made of stabilised native collagen type I and a silicone sheet of about 200 mm thickness mechanically reinforced with a polyester fabric. No glycosaminoglycan (GAG) added to improve cell attachment and proliferation |
A silicone layer on top of a porous matrix comprising a chemically cross‐linked coprecipitate of bovine collagen and shark‐derived chondroitin‐6‐sulphate (GAG) |
| The extraction procedure and the freeze drying process allow the structuring of the collagen into a matrix with optimal hydrophilicity, pore structure, and pore size (20‐125 μm) |
The Integra pore size of 20 to 125 μm allows influx of cells |
| It is cellularised by patient own cells in 2 to 3 weeks after implant. The silicone layer is removed after dermal regeneration (21 days) at the time of the thin split‐thickness skin graft |
The dermal template usually becomes revascularised within 21 days after grafting; at this point, the silicon sheet can be removed, and a split‐thickness skin graft can be applied |
| Is used for dermal regeneration in skin loss, especially in burns surgery (third‐ and deep second‐degree burns and burns sequelae), chronic wounds surgery (including leg ulcers and diabetic foot), traumatology, skin tumours surgery, reconstructive plastic surgery, and in children. Is used in combination with a thin split‐thickness skin graft |
Is used for burns treatment and for full‐thickness burns, chronic ulcers, full‐thickness non‐thermal skin wound management, plastic and reconstructive surgery, in skin tumours surgery, post‐traumatic injury. Is used in combination with a thin split‐thickness skin graft for soft tissues repair |
