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. 2017 Jul 20;14(6):1225–1236. doi: 10.1111/iwj.12789

Figure 4.

IWJ-12789-FIG-0004-c

Staining of CD68 and CD18 inflammatory cells in normal skin and venous leg ulcer biopsies. (A) Montage of a section from a 4‐mm biopsy from normal arm skin and (B) the edge of a venous leg ulcer stained for CD68 (purple). (C) Higher‐power images taken in the upper dermis at the wound edge (WE) 1 mm in and at the far edge (FE). Graphs showing counts of CD68‐positive cells demonstrated a significant (P < 0·001 WE & 1 mm and FE P < 0·01) elevation compared to normal skin biopsies. (D) Montage of a section from a 4‐mm biopsy from normal arm skin and (E) the edge of a venous leg ulcer stained for CD18 (purple). (F) Higher‐power images taken in the upper dermis at the wound edge (WE) 1 mm in and at the far edge (FE). (H) Graphs showing counts of CD18‐positive cells demonstrated a significant (P < 0·01 WE, P < 0·05 FE) elevation compared to normal skin biopsies. Error bars: mean ± SEM. Arrow and WE mark the wound edge. Scale bars, montage 500 µm and high power 100 µm.