Table 1.
S100A8/A9 in wound biopsies (ρg/ml ± SD). Impact of Pseudomonas aeruginosa biofilm infection on S100A8/A9 levels (ρg/ml ± SD) in central and peripheral wound biopsies. BALB/c mice have significantly more S100A8/A9 centrally in infected wounds (P < 0·018). C3H/HeN mice have reduced peripheral levels of S100A8/A9 from 4 to 7 days post‐infection (DPI) (P < 0·024)
| BALB/c | C3H/HeN | ||||
|---|---|---|---|---|---|
| DPI | Localisation | Infected (n = 6) | Non‐infected (n = 3) | Infected (n = 6) | Non‐infected (n = 3) |
| 4 | Central | 3568 (±1144)* | 6307 (±434·3) | 2105 (±461·1)* | 2497 (±923·2) |
| 7 | Central | 24 547 (±50 924) | 5600 (±2913) | 2390 (±1014) | 20 403 (±26 473) |
| 10 | Central | 6918 (±9693) | 4253 (±2536) | 1905 ± (701·7) | 2453 (±503·4) |
| 4 | Peripheral | 7370 (±10 417) | 4072 (±310·1) | 3152 (±1477)† | 2097 (±853·5) |
| 7 | Peripheral | 23 265 (±51 636) | 8057 (±10 103) | 1465 (±471·5)† | 3073 (±947·1) |
| 10 | Peripheral | 2947 (±1757) | 8847 (±9654) | 2387 (±900·6) | 3440 (±1488) |
*
Significant difference between strains.
†
Significant decrease in S100A8/A9 levels from 4 to 7 DPI in C3H/HeN mice.