Figure 3.

In situ visualisation of biofilm in wound tissue. Fluorescent in situ Hybridisation shows bacterial cells (red) attached to the host wound debridement tissue (blue ‐DAPI). A, Acute wound. B, Chronic wound with bacterial biofilm. C, Isometric view showing biofilm clusters attached to the chronic wound host tissue. Scanning Electron Microscopy (SEM) images of (D) acute wound with planktonic bacterial cells, 5000×; (E and F) Chronic wound with clustered bacterial biofilm, 5000× and 3000×, respectively