Figure 2.

Representative Masson's trichrome stained sections from vitamin C (VitC) sufficient, deficient, and deficient + AscA Gulo^−/− mice at day 7 (A–C) and day 14 (D–F) post‐wounding. VitC sufficient (A) and deficient + AscA (C) sections demonstrated more dense granulation tissue with significant collagen deposition (blue colour) and distinct lamina. In contrast, sections from the deficient mice were more cellular with loose granulation tissue and reduced collagen deposition (B). Also the lamina remained indistinct. Similar observations were evident from day‐14 sections (D–F) with the VitC deficient mice group still showing considerably reduced collagen deposition (n = 3–6 mice per group).