Table 5.
Diabetic‐induced excision wound‐healing activity of Cb‐peptide
| Groups | Wound contraction (mm)2 | |||||
|---|---|---|---|---|---|---|
| Day 0 | Day 5 | Day 10 | Day 15 | Day 21 | Period of epithelisation | |
| Vehicle control | 86.3 ± 3.1 (0.00) | 80.16 ± 2.70 (6.97) | 56.1 ± 3.40 (34.88) | 50.1 ± 2.14 (41.86) | 25.27 ± 2.66 (70.93) | 30.24 ± 0.36 |
| Standard control | 85.5 ± 6.5 (0.00) | 52.1 ± 3.17b (38.82) | 14.1 ± 2.05c (83.52) | 0.00 (100) | 0.00 (100) | 14.18 ± 0.3 |
| Cb‐peptide high dose | 85 ± 3.8 (0.00) | 47.1 ± 4.43a (44.70) | 3.66 ± 2.3c (96.47) | 0.00 (100) | 0.00 (100) | 12 ± 0.2 |
| Cb‐peptide low dose | 86.5 ± 2.8 (0.00) | 50.66 ± 1.62c (41.86) | 10.5 ± 0.5c (88.37) | 0.00 (100) | 0.00 (100) | 13.50 ± 0.4 |
Values are expressed as mean ± SEM, n = 6; 1‐way ANOVA followed by Dunnett's t‐test; t‐values denotes significance at (a) P < .05; (b) P < .1; (c) P < .001. Percentage of would contraction presented in parenthesis.