Fig. 7.
Cellular survival in the presence of protein misfolding stress.A, the response to AZC treatment in dividing mouse (red) and naked mole rat (blue) cells. Cell viability represents the fraction of live cells in treated cells relative to untreated cells. B, the response to AZC treatment in quiescent mouse (red) and naked mole rat (blue) cells. Cell viability represents the fraction of cells that excluded trypan blue. Error bars indicate SD. ∗p-value < 0.05. AZC, azetidine-2-carboxylic acid.