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. 2021 Feb 22;13(4):6115–6133. doi: 10.18632/aging.202606

Figure 5.

Figure 5

Expression of let-7e affected the growth and proliferation of HCC cells. (A) Results of cell viability assays showed that upregulated let-7e promoted the proliferation of HepG2 and Hep3B HCC cells. (B) Colony formation assays revealed that upregulated let-7e improved the colony formation efficiency of HepG2 and Hep3B HCC cells. (C) Downregulated let-7e inhibited the proliferation of HepG2 and Hep3B HCC cells. (D) Downregulated let-7e inhibited the colony formation efficiency of HepG2 and Hep3B HCC cells (*P<0.05, **P<0.01, ***P<0.001). NC mimic–transfected and NC inhibitor–transfected cells were the control group in all experiments.