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. 2021 Feb 22;13(4):6115–6133. doi: 10.18632/aging.202606

Table 2. Association between let-7e expression and clinicopathological parameters in HCC.

Variable Patients (n) N=63 Let-7e expression (qPCR) P value
Low(n=31) High(n=32)
Age 0.701
<60 30 14 16
≥60 33 17 16
Gender 0.260
Male 35 15 20
Female 28 16 12
Child-Pugh 0.719
A 38 18 20
B 25 13 12
Liver cirrhosis 0.124
yes 43 24 19
no 20 7 13
Differentiation 0.014
Well-moderate 23 16 7
Poor 40 15 25
Tumor size 0.029
≤5cm 36 22 14
>5cm 27 9 18
Venous invasion 0.031
Positive 37 14 23
Negative 26 17 9
BCLC stage 0.539
A 17 10 7
B 33 16 17
C 13 5 8
AFP level 0.532
<400 33 15 18
>400 30 16 14

Notes: P < 0.05 by χ2 test. P < 0.05 was considered statistically significant.

Abbreviations: BCLC, Barcelona Clinic Liver Cancer; AFP, alpha-fetoprotein.