Table 2. Association between let-7e expression and clinicopathological parameters in HCC.
Variable | Patients (n) N=63 | Let-7e expression (qPCR) | P value | |
Low(n=31) | High(n=32) | |||
Age | 0.701 | |||
<60 | 30 | 14 | 16 | |
≥60 | 33 | 17 | 16 | |
Gender | 0.260 | |||
Male | 35 | 15 | 20 | |
Female | 28 | 16 | 12 | |
Child-Pugh | 0.719 | |||
A | 38 | 18 | 20 | |
B | 25 | 13 | 12 | |
Liver cirrhosis | 0.124 | |||
yes | 43 | 24 | 19 | |
no | 20 | 7 | 13 | |
Differentiation | 0.014 | |||
Well-moderate | 23 | 16 | 7 | |
Poor | 40 | 15 | 25 | |
Tumor size | 0.029 | |||
≤5cm | 36 | 22 | 14 | |
>5cm | 27 | 9 | 18 | |
Venous invasion | 0.031 | |||
Positive | 37 | 14 | 23 | |
Negative | 26 | 17 | 9 | |
BCLC stage | 0.539 | |||
A | 17 | 10 | 7 | |
B | 33 | 16 | 17 | |
C | 13 | 5 | 8 | |
AFP level | 0.532 | |||
<400 | 33 | 15 | 18 | |
>400 | 30 | 16 | 14 |
Notes: P < 0.05 by χ2 test. P < 0.05 was considered statistically significant.
Abbreviations: BCLC, Barcelona Clinic Liver Cancer; AFP, alpha-fetoprotein.