Table 1. Significance (p-value) and slope of the variation in CBF as a function of age and sex for the linear regression analysis for each GM and WM brain region studied.
NESMA filtered | Unfiltered | ||||||||||||||||
Gray matter (GM) | White matter (WM) | Gray matter (GM) | White matter (WM) | ||||||||||||||
Age | Sex | Age | Sex | Age | Sex | Age | Sex | ||||||||||
p-value | Slope | p-value | Slope | p-value | Slope | p-value | Slope | p-value | Slope | p-value | Slope | p-value | Slope | p-value | Slope | ||
Whole Brain | < 0.01 | -0.11 | < 0.01 | -4.95 | < 0.01 | 0.08 | < 0.05 | -1.90 | < 0.01 | -0.11 | < 0.01 | -4.92 | < 0.01 | 0.07 | < 0.1 | -1.41 | |
Frontal Lobes | < 0.01 | -0.16 | < 0.01 | -3.85 | < 0.05 | 0.04 | < 0.05 | -1.44 | < 0.01 | -0.15 | < 0.01 | -3.85 | < 0.05 | 0.02 | > 0.1 | -1.04 | |
Occipital Lobes | < 0.05 | -0.10 | < 0.01 | -8.32 | < 0.01 | 0.06 | < 0.01 | -2.56 | < 0.1 | -0.10 | < 0.01 | -8.35 | < 0.01 | 0.04 | < 0.01 | -1.96 | |
Parietal Lobes | < 0.1 | -0.08 | < 0.01 | -5.20 | < 0.01 | 0.06 | < 0.05 | -1.66 | > 0.1 | -0.08 | < 0.01 | -5.32 | < 0.05 | 0.04 | < 0.05 | -1.20 | |
Temporal lobes | < 0.05 | -0.07 | < 0.01 | -4.82 | < 0.01 | 0.05 | < 0.01 | -1.84 | < 0.05 | -0.07 | < 0.01 | -4.82 | < 0.05 | 0.03 | < 0.01 | -1.34 | |
Cerebellum | < 0.05 | -0.09 | < 0.01 | -5.64 | < 0.05 | 0.04 | < 0.01 | -2.12 | < 0.1 | -0.10 | < 0.01 | -5.38 | < 0.05 | 0.02 | < 0.01 | -1.85 |
All p-values presented are obtained after FDR correction. Results are shown for both CBF maps derived with or without the NESMA filtering of the ASL images.