Table 1. Basic characteristics of aneurysm rupture and NLR in patients with intracranial aneurysm.
Characteristics | rIAs | uIAs | p | ||
NLR<4 (n=76) | NLR≥4 (n=72) | NLR<4 (n=363) | NLR≥4 (n=21) | ||
Age, y; mean (SD) | 51.78 (10.22) | 55.11 (12.57) | 54.23 (10.02) | 53.76 (10.56) | 0.218 |
Women (%) | 43 (56.6) | 37 (51.4) | 234 (64.5) | 18 (85.7) | 0.016 |
Medical history, n (%) | |||||
Stroke, n (%) | 9 (11.8) | 6 (8.3) | 36 (9.9) | 0 (0.0) | 0.461 |
Hypertension | 36 (47.4) | 45 (62.5) | 173 (47.7) | 12 (57.1) | 0.115 |
Hyperlipidemia | 6 (7.9) | 2 (2.8) | 48 (13.2) | 0 (0.0) | 0.012 |
Diabetes mellitus | 4 (5.3) | 3 (4.2) | 38 (10.5) | 4 (19.0) | 0.074 |
Heart disease | 3 (3.9) | 4 (5.6) | 20 (5.5) | 2 (9.5) | 0.707 |
Current smoking, n (%) | 17 (22.4) | 27 (37.5) | 67 (18.5) | 2 (9.5) | 0.003 |
Size, mm; median (IQR) | 5.23 [3.89, 7.96] | 4.91 [3.52, 6.91] | 5.93 [4.09, 9.79] | 9.90 [6.00, 15.30] | <0.001 |
Location, n (%) | |||||
Anterior circulation | 12 (15.8) | 3 (4.2) | 55 (15.2) | 1 (4.8) | 0.033 |
Posterior circulation | 64 (84.2) | 69 (95.8) | 308 (84.8) | 20 (95.2) | |
Modified fisher grade, n (%) | |||||
0-2 | 59 (77.6) | 46 (63.9) | NaN | NaN | NaN |
>2 | 17 (22.4) | 26 (36.1) | NaN | NaN | |
Laboratory parameter | |||||
WBC, 109/L; median (IQR) | 6.46 [5.19, 7.65] | 10.55 [8.35, 12.61] | 5.94 [5.13, 7.07] | 8.13 [7.10, 9.31] | <0.001 |
NEUT, 109/L; median (IQR) | 3.86 [2.92, 4.70] | 8.57 [6.85, 10.93] | 3.45 [2.75, 4.23] | 6.29 [5.71, 7.44] | <0.001 |
LY, 109/L; mean (SD) | 2.06 (0.60) | 1.14 (0.47) | 2.02 (0.58) | 1.15 (0.44) | <0.001 |
NLR, median (IQR) | 1.83 [1.47, 2.46] | 7.34 [5.80, 10.90] | 1.77 [1.37, 2.30] | 5.60 [4.52, 6.64] | <0.001 |
CRP, mg/L; median (IQR) | 2.53 [1.90, 3.01] | 9.10 [6.73, 11.70] | 2.44 [1.61, 2.93] | 4.27 [3.61, 5.52] | <0.001 |
HDL, mmol/L; mean (SD) | 1.23 (0.33) | 1.38 (0.36) | 1.31 (0.33) | 1.34 (0.38) | 0.105 |
LDL, mmol/L; mean (SD) | 2.83 [2.15, 3.42] | 2.66 [2.29, 3.54] | 2.84 [2.20, 3.49] | 2.85 [2.06, 3.72] | 0.958 |
TG, mmol/L; median (IQR) | 1.48 [0.90, 1.93] | 1.20 [0.97, 1.71] | 1.29 [1.00, 1.87] | 1.21 [0.76, 2.02] | 0.597 |
Apo-A1, g/L; mean (SD) | 1.35 (0.29) | 1.41 (0.32) | 1.48 (0.27) | 1.46 (0.28) | 0.008 |
Apo-B, g/L; mean (SD) | 0.87 (0.22) | 0.92 (0.24) | 0.93 (0.24) | 0.93 (0.24) | 0.404 |
Body temperature, ° C; mean (SD) | 37.6 (7.31) | 38.1 (6.95) | 36.4 (3.85) | 36.7 (3.92) | 0.028 |
Treatment Modality, n (%) | |||||
Coiling only | 50 (65.8) | 61 (84.7) | 118 (32.5) | 4 (19.0) | NA |
Stent-assisted coiling or sole stenting | 26 (34.2) | 10 (13.9) | 235 (64.7) | 17 (81.0) | |
Balloon-assisted coiling and others | 0 (0.0) | 1 (1.4) | 10 (2.8) | 0 (0.0) |
rIAs, ruptured intracranial aneurysms; uIAs, unruptured intracranial aneurysms; NLR, neutrophil-lymphocyte ratio; WBC, white blood cell; NEUT, neutrophil; LY, lymphocyte; CRP, C-reactive protein; HDL, high density lipoprotein; LDL, low density lipoprotein; TG, triglyceride; ApoA-1, apolipoprotein A-I; and Apo-B, apolipoprotein B.